55 photos · MLS data verified October 9, 2026 · Updated every 15 min
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$998,888
Active
3 Beds·4 Baths·1,630 sqft·3,500 sqft lot·Built 1895
643 Grand Ave, South San Francisco, CA 94080
Listed 43 days ago · | MLS# ML82059314
$612/sqft
643 Grand Ave is a 3-bedroom, 4-bath single family home in South San Francisco 94080 with 1,630 square feet of living space, built in 1895. It is listed at $998,888, or $612 per square foot. The three most recent 3-bedroom sales in 94080 closed between $950,000 and $1,480,000 ($791 to $1,101 per square foot).
Est. $6,486/moP&I $5,183 · Tax $1,041 · Insurance $262 · HOA $0Assumes 20% down ($199,778) at 6.75% · Contact Timothy for a lender referralAegis Luxury Real Estate is a licensed California real estate brokerage (DRE# 01328224) and is not a mortgage lender, mortgage broker, or loan originator. The figures shown are estimates for general reference only and do not constitute a loan offer, pre-approval, pre-qualification, or commitment to lend. Estimates use a property tax rate of 1.25% of home price annually. Actual rates, payments, taxes, and insurance vary by lender and borrower qualifications. Contact Timothy for a referral to one of our preferred lending partners.
Single Family Price Position in South San Francisco
$1.1M$1.7M
31Active in South San Francisco
21Active Single Family Homes
2.8 moInventory
Why This Home Stands Out
🏠
3 Bed / 4 Bath, 1,630 sqft
Built in 1895, 2-car garage.
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Best fit forActive BuyersSouth San Francisco SearchersMove-Up / Move-In
About 643 Grand Ave
Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging and an additional 2 car off street parking in front of the house. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.
MLS ID #ML82059314, Jill Penna. Listing provided by Christie's International Real Estate Sereno · MLSListings Inc.
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Property Details for 643 Grand Ave
Overview
- Property Type
- Single Family Residence
- Year Built
- 1895
- Stories
- 2
- Bedrooms
- 3
- Bathrooms
- 4 Full
- Living Area
- 1,630 sqft
- Lot Size
- 3,500 sqft (0.08 acres)
- Price/sqft
- $612
- Status
- Active
Interior
- Primary Bedroom
- Ground floor
- Kitchen
- Dining areain living room
- Appliances
- Dishwasher, Garbage disposal, Refrigerator, Washer dryer, Water softener
- Heating
- Central forced air
- Cooling
- None
- Flooring
- Hardwood
- Family Room
- None
- Interior Features
- One or more skylights, Walkin closet
Exterior and Parking
- Garage
- Garage, 2 spaces
- Roof
- Shingle
- Foundation
- Concrete slab
- Zoning
- Rm0000
Community and HOA
- Utilities
- Public, Water public
- County
- San Mateo
- City
- South San Francisco
Schools
- School District
- South San Francisco Unified
- South San Francisco Schools
- View South San Francisco schools
Listing
- MLS Number
- ML82059314
- Listed
- August 27, 2026
- Days on Market
- 43
- Listing Agent
- Jill Penna
- Listing Brokerage
- Christie's International Real Estate Sereno
- Data Verified
- October 9, 2026
Source: MLSListings Inc. School attendance boundaries are set by the district and can change; verify directly with the district.
Free from Aegis · Updated for October 2026
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📄South San Francisco Market ReportFree 9-page PDF with bedroom breakdowns, comp data and pricing trends, updated monthly.Email Me the Report →📋South San Francisco Buyer BriefA personalized brief with comp data, offer strategy and neighborhood context.Email Me the Report →🎯South San Francisco Offer StrategyComp analysis and bid recommendations before you write an offer on this home.Email Me the Report →
Location
643 Grand Ave, South San Francisco, CA 94080 · San Mateo County
Market Context
Price Positioning
🏠 Inventory: 11 3-bedroom homes and 21 single family homes currently active in South San Francisco.
Source: MLSListings Inc. Timothy Alston, Broker, DRE# 01328224.
Want to know what this home will actually sell for? Get a data-backed offer range based on recent comparable sales.
Get My Offer Range →Frequently Asked Questions
Listed at $998,888 ($612/sqft). The three most recent 3-bedroom sales in 94080 closed at $791 to $1,101 per sqft.
Listed August 27, 2026. That is 43 days on market as of October 9, 2026.
Est. $6,486/mo with 20% down ($199,778) at 6.75%. That is principal and interest $5,183, property tax $1,041 and insurance $262. The assumptions and lender disclosure are with the payment estimate at the top of this page.
There are 31 active listings in South San Francisco: 11 are 3-bedroom and 21 are single family homes.
The three most recent 3-bedroom sales in South San Francisco 94080 closed at $950,000, $1,079,000 and $1,480,000, or $791 to $1,101 per sqft.
Yes. As of October 9, 2026, 643 Grand Ave is an active listing at $998,888. It is a 3-bedroom, 4-bath single family home.
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Broker · DRE# 01328224 · Over 23 Years Experience
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Buyers
See 643 Grand Ave before the weekend
Listed 43 days ago.
Questions
Talk to Timothy directly
Timothy Alston, Broker, DRE# 01328224. Over 23 years in Silicon Valley real estate.
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